CHARACTERISTICS MULTIPLE DRUGS RESISTANCE PATIENT THAT CONVERSION CULTURES AT FIRST MONTHS OF TREATMENT IN dr. SOETOMO SURABAYA HOSPITAL

Abstract

Multiple Drug Resistant Tuberculosis (MDR TB) is one of the TB bacterial resistance to at least two first-line anti-TB drugs, Isoniazid and Rifampicin  which are the two most effective TB drugs. Sputum culture conversion and is an indicator of treatment response. In this study we investigate characteristics of MDR TB patients who experience culture conversion in the first month of therapy at the Dr. Soetomo Hospital. Descriptive research design, consecutive sampling techniques, using questioner and medical records of MDR TB patients during January 2014 until September 2015, the number of respondents 43 people. Results of the research are 13 people (30.23%) 41-50 years age group, 22 (51%) male gender, 23 people (53%) of high school education, 24 (55.81%) it’s not working, 21 people (48.84 %) duration of therapy tuberculosis 6 months, 9 (20.93%) duration treatment of MDR TB at third month the first year of therapy, 16 (84.38%) comorbid Diabetes Mellitus, 31 (72.09%) culture results negative in the second month therapy, 17 (39.53%) experienced a conversion in the first month of monitoring, 23 people (53.49%) patients nutritional status skinny, 27 (62.79%) non-adherent patients, 27 (62.79%) said that the cost is not burdensome. Conversion culture is the result of negative culture examination twice in a row, can be affected by several factors, including nutritional status, presence of comorbidities, patient compliance. Diagnosis and implementation of appropriate therapy according to directive officer can help improve the condition of the patient, so that the conversion time can be cultured in accordance with the purpose of treatment.